Banting e Charles Best administraram a primeira injeção de insulina em um paciente com diabetes tipo 1.

Leonard Thompson era um menino de 14 anos com um diagnóstico de diabetes há dois anos que era mantido vivo essencialmente passando fome. Ele entrava e saía do coma diabético constantemente e pesava apenas 30 quilos.

O pai de Leonard concordou que seu filho deveria ser o primeiro a testar a insulina, o que nunca havia sido testado em outro ser humano. Em 11 de janeiro de 1922, Banting e Best levaram o extrato de insulina para a Ala H do Hospital Geral de Toronto e a primeira injeção de insulina foi administrada a Leonard Thompson por um estagiário. A glicemia de Leonard caiu de 440mg/dL para 320 mg, mas ele desenvolveu um abscesso estéril e outras

injeções foram canceladas.

Trabalhos adicionais foram realizados para purificar o extrato de forma reprodutiva e Leonard posteriormente recebeu uma injeção às 11h do dia 23 de janeiro, uma segunda dose naquela noite e duas injeções no dia seguinte. Desta vez foi um sucesso total e os níveis de açúcar no sangue de Leonard voltaram ao normal, sem efeitos colaterais óbvios.

Pela primeira vez na história, o diabetes tipo 1 não foi uma sentença de morte. Leonard Thompson

apresentou sinais de melhora na saude e viveu mais 13 anos tomando doses de insulina. Infelizmente, ele

morreu de pneumonia aos 27 anos.

Antes da insulina ser disponibilizada clinicamente, o diagnóstico de diabetes tipo 1 era uma sentença de morte. A descoberta da insulina transformou completamente o tratamento da diabetes, salvando milhões de vidas em todo o mundo.

E graças à descoberta de Banting que mais de 537 milhões de pessoas com diabetes em todo o mundo conseguem viver.

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